Bioconversion of α-pinene by a novel cold-adapted fungus Chrysosporium pannorum
نویسندگان
چکیده
منابع مشابه
Chrysosporin, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase produced by Chrysosporium pannorum.
Cholesterol is synthesized via more than 20 enzymatic reactions. This pathway is mainly regulated by the enzyme, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)reductase1}. Recent clinical results have shown that HMG-CoA reductase inhibitors such as lovastatin2) (monacolin K3)) are safe and effective drugs for treatment of hypercholesterolemia4). Wehave previously reported that Chrysosporium pa...
متن کاملPannorin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor produced by Chrysosporium pannorum.
Pannorin, a naphthopyrone that inhibits 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme in cholesterol synthesis, was isolated from a culture broth of Chrysosporium pannorum M10539 by solvent extraction, Bio-Gel P-6 column chromatography and reverse phase HPLC (Silica ODS). Spectroscopic analyses of the compound yielded 4,8,10-trihydroxy-5-methyl-2H-naphtho[1...
متن کاملUnanticipated Stickiness of α-Pinene.
The adsorption of α-pinene to solid surfaces is an important primary step during the chemical conversion of this common terpene over mesoporous materials, as well as during the formation of atmospheric aerosols. We provide evidence of tight and loose physisorbed states of α-pinene bound on amorphous SiO2 as determined by their adsorption entropy, enthalpy, and binding free energies characterize...
متن کاملBiological activities of α-pinene and β-pinene enantiomers.
The antimicrobial activities of the isomers and enantiomers of pinene were evaluated against bacterial and fungal cells. The agar diffusion test showed that only the positive enantiomers of the α- and β-isomers of pinene were active. The minimal inhibitory concentration (MIC) and minimal microbicidal concentration (MMC) of these monoterpenes were also determined, confirming that the positive en...
متن کاملPurification and characterization of a novel cold adapted fungal glucoamylase
BACKGROUND Amylases are used in various industrial processes and a key requirement for the efficiency of these processes is the use of enzymes with high catalytic activity at ambient temperature. Unfortunately, most amylases isolated from bacteria and filamentous fungi have optimal activity above 45 °C and low pH. For example, the most commonly used industrial glucoamylases, a type of amylase t...
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ژورنال
عنوان ژورنال: Journal of Industrial Microbiology and Biotechnology
سال: 2015
ISSN: 1476-5535,1367-5435
DOI: 10.1007/s10295-014-1550-0